Asbestosis and silicosis

Silicosis and Asbestosis

Mechanisms in the pathogenesis of asbestosis and silicosis.

Interstitial pulmonary fibrosis caused by the inhalation of asbestos fibers or silica particles continues to be an important cause of interstitial lung disease. Although more stringent control of asbestos in the workplace and decreasing industrial use has contributed to declines in the prevalence of asbestosis in the United States (1), new cases continue to be identified. Similarly, silicosis i...

Iron, Oxidative Stress, and Cell Signaling in the Pathogeneses of Coal Workers’ Pneumoconiosis, Silicosis, and Asbestosis

Coal workers’ pneumoconiosis (CWP), silicosis, and asbestosis were the most common occupational diseases in the 20 th Century. The passage of the Mine Health and Safety Act in 1968 resulted in reduction of occupational exposures to coal, silica, and asbestos fibers and, thus, decreased incidence of the diseases. However, the most recent data showed that, from the beginning of the 21 st Century,...

An overview of the role of mineral solubility in silicosis and asbestosis.

Asbestosis and silicosis are fibrotic diseases initiated by the inhalation of silica-containing dusts, asbestos and quartz. There are various approaches for explaining the causes of these diseases. At present, our knowledge on the matter indicates that silicic acid dissolved from these minerals, contact between macrophages and minerals, highly reactive and oxidative species formed on the minera...

Descriptive review of asbestosis and silicosis hospitalization trends in North Carolina, 2002-2011.

BACKGROUND Asbestosis and silicosis are debilitating pulmonary conditions resulting from inhalation of asbestos fibers or silica dust. PURPOSE We provide a descriptive analysis of asbestosis and silicosis hospitalizations in North Carolina to assess trends over a 10-year period. METHODS Events were defined as inpatient hospital discharges during the period 2002-2011 with an International Cl...